$re = '/.*(SomeMethod)\s([^\']+)\s.*/';
$str = 'SomeMethod x, 5, True \'Optional Comments
**SomeMethod x, 5, True \'Optional Comments that I don\'t mind throwing away if it makes things easier';
$subst = "$1($2)";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php