$re = '/\b(?!(?:JOHN|I)\b)(?:[A-Z]{1,8}[0-9]?|[0-9]{2,3})\b/';
$str = 'JOHN went to LONDON one fine day. JOHN had lunch in a PUB. JOHN then moved to CHICAGO. I don\'t want JOHN to be highlighted. John does not want this to match the pattern. Neither this. But THIS1 should match the pattern. Also the other 70 times that the pattern should match.';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php