$re = '/\$|\,|\(|\)|@|\./';
$str = '$16,500,000(@$2,500)
$34,000(@$11.00)
$214,000(@$18.00)
$12,684,000(@$3,800) ';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php