$re = '/([\s\S].*?)(<.+>)/m';
$str = '<span id="3">
HELLO THERE
<span id="5">
Other stuff
<span id="6">
Other Stuff
<span id="7">
Other sutff';
$subst = "$2";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php