$re = '/^.*\/|\?.*$/m';
$str = 'www.website.com/dsw/fv3n24nv1e4121v/123456789012?fwe=32432fdwe23f3';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php