use strict;
my $str = 'https://www.youtube.com/watch?v=hMZ0Q7Yio8g&list=RDhMZ0Q7Yio8g&start_radio=1';
my $regex = qr/https:\/\/www\.youtube\.com\/watch\?v=hMZ0Q7Yio8g&list=RDhMZ0Q7Yio8g&start_radio=1/p;
my $subst = 'red';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html