# If you'd like to omit non-matching lines from the result; add ';d' to the end of the expression.
sed -E 's/^(?:.*?\K\/\/){3}/\\\\/gm;t' <<< "ABC//DEG//IJK//LMN//OPQ//rstuvwxyz
BCA//EGD//JKI//MNL//PQO//stuvwxyzr
ACB//DGE//IJK//LNM//OQP//rstuvwxyz
ABC//DEG//IJK//LMN//OPQ//rstuvwxyz
CAB//GDE//KIJ//NLM//QOP//rstuvwxyz
BAC//EDG//JIK//MLN//POQ//rstuvwxyz"
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for SED, please visit: https://www.gnu.org/software/sed/manual/html_node/The-_0022s_0022-Command.html