const regex = new RegExp('^(?:.*?\\K//){3}', 'gm')
const str = `ABC//DEG//IJK//LMN//OPQ//rstuvwxyz
BCA//EGD//JKI//MNL//PQO//stuvwxyzr
ACB//DGE//IJK//LNM//OQP//rstuvwxyz
ABC//DEG//IJK//LMN//OPQ//rstuvwxyz
CAB//GDE//KIJ//NLM//QOP//rstuvwxyz
BAC//EDG//JIK//MLN//POQ//rstuvwxyz`;
const subst = `\\\\`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions