$re = '/([0-9]+)\s([A-Za-z0-9\-\s]+)\,\s([A-Za-z\s]+)\,\s([A-Z]{2})\s([0-9\-]{5,10})/m';
$str = '123 Riverview Pkwy, Orlando, FL 55556
12 Street Pkwy, Miami, FL 98989
18 Street Pkwy, TAMPA, FL 80148-0980
18 Street 76 PKWY, TAMPA, FL 80148-0980
18 Goerge-Washington Street 76 Pkwy, Tampa, FL 80148-0980
18 Street Pkwy, Tampa, FL 80148-0980989';
$subst = "$2 $3 $4 $5";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php