$re = '/(?:(?:http|https):\/\/)?(?:www.)?(?:instagram.com|instagr.am|instagr.com)\/(\w+)/im';
$str = 'http://instagram.com/username
http://instagram.com/username?modal=true
https://instagram.com/username
https://instagram.com/username?modal=true
http://www.instagram.com/username
http://www.instagram.com/username?modal=true
https://www.instagram.com/username
https://www.instagram.com/username?modal=true
instagram.com/username
instagram.com/username?modal=true
www.instagram.com/username
www.instagram.com/username?modal=true
http://instagr.am/username
http://instagr.am/username?modal=true
http://www.instagr.am/username
http://www.instagr.am/username?modal=true
https://instagr.am/username
https://instagr.com/username
https://instagr.am/username?modal=true
https://www.instagr.am/username
https://www.instagr.am/username?modal=true';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php