$re = '/(?<=^\P{L}*)(?<!\d)\d{2,10}(?!\d)/m';
$str = '2216101225 /ROC/PL FCT DIN 24.03.2022 PL ERBICIDE
++++ 2216101225 :: 23467 -- 432423423423423 444/ROC/PL FCT DIN 24.03.2022 PL ERBICIDE';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php