$re = '/^A(?:(?![A-Z]{2}).)*?\K\d+/m';
$str = 'A bcd 1 should match and capture 1
Abcd1 should match and capture 1
A bcd should not match because there is no number
A BCd 1 should not match because there is a capital C between the A and the number
A bcd 1 EF should match because 1 is before the EF';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php