$re = '/^[ \-a-zA-Z.]+\s+(\d+(\s?\w$)?)/m';
$str = 'Lilienstr. 12a
Hagentorwall 3
Seilerstr. 14 (Eingang Birkenstr.)
Guentherstr. 43 B
Eberhard-Leibnitz Str. 1 WH 5B 241
1019-1781 Borderlinx C/O SEKO Logistics
';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php