#include <MsgBoxConstants.au3> ; to declare the Constants of MsgBox
Local $sRegex = "(?m)(https:\/\/www.myurl.com\/)([A-Za-z0-9-]+)(\/\smarker needle)"
Local $sString = "line = '[text] something - https://www.myurl.com/test1/ lorem ipsum https://www.myurl.com/test2/ - https://www.myurl.com/test3/ marker needle - some more text at the end'" & @CRLF & _
""
Local $sSubst = ""
Local $sResult = StringRegExpReplace($sString, $sRegex, $sSubst)
MsgBox($MB_SYSTEMMODAL, "Result", $sResult)
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for AutoIt, please visit: https://www.autoitscript.com/autoit3/docs/functions/StringRegExp.htm