use strict;
my $str = 'Dios mÃo, ¡está aquÃ, está aquÃ, está aquÃ!
¿Qué paso, qué paso?
Me rehúso, me rehúso.
No, no, no, no.';
my $regex = qr/([\W\S]\s[\w\W]{2}.+),\s(.+)\1([!?.])/mip;
my $subst = '$1$3';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html