const regex = new RegExp('(?s).*\\b(http://www\\.blooming\\.com\\b.*?\\.jpg\\b).*', '')
const str = `<div>Colorful Floor chair Series</div><div><br /></div><div>Soft
Suede</div><div><br /></div><div>Cute bubble design</div><div><br
/></div><div><p align="center"><p align="center"><img
src="http://gdetail.image-gemkt.com/186/716088198/2010/2/e3b117e2-a7bd-4d.GIF"
/></div><div><p align="center"><p align="center"><img
src="http://www.blooming.com/image/xxxxxxxx.jpg" /></div>`;
const subst = `\1`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions