$re = '%/mnt/pond/processed/industry-data/anadarko/lucius/inspections/20191214/(.+)/sphericals/(.+)/(.{22}).([0-9].jpg)%';
$str = '/mnt/pond/processed/industry-data/anadarko/lucius/inspections/20191214/cubes/sphericals/TS/TS7013.col-panorama_sh.4.jpg';
$subst = "/mnt/pond/processed/industry-data/anadarko/lucius/inspections/20191214/images/\1/rgb/4096/\2/\3/\4";
$result = preg_replace($re, $subst, $str, 1);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php