const regex = /(?!\B"[^"]*),(?![^"]*"\B)/gm;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('(?!\\B"[^"]*),(?![^"]*"\\B)', 'gm')
const str = `aaa,bbb,ccc,"ddd,eee","fff,ggg"
"aaa,bbb",ccc,ddd,"eee,fff"
"aaa,bbb","ccc,ddd","eee,fff",ggg
`;
const subst = `\|`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions