$re = '/^(?:[0-9]*\s*[pP](?:\.O\.|o)(?:st(?:al)?\soffice\s)*[bB]ox(?:\sstreet)?)$/m';
$str = 'P.O.Box
pobox
post office box
box
BOX
poor box etc.,
1234 post office box street
123 postal office box
';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php