use strict;
my $str = 'C:\\Program Files\\nodejs\\node_modules
C:\\nodejs\\node_modules
C:\\Program Files\\test\\nodejs\\node_modules
';
my $regex = qr/^[A-Z]:\\(?:[^\\\n]*\\)*([^\\\n]+)\\([^\\\n]+)$/mp;
my $subst = 'http:s//$1/$2';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html