$re = '/begin(?:(?!begin).)*TOKEN_456.*?end/is';
$str = 'someText
begin
.someMethod()
.doSomething(TOKEN_123)
.someMethod()
end
begin
.someMethod()
.doSomething(TOKEN_456)
.someMethod()
end
begin
.someMethod()
.doSomething(TOKEN_789)
.someMethod()
end
more Text';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php