$re = '/(?:[^(|)]*+(\((?:[^()]++|(?1))\))?+)*+\K\|/';
$str = 'example|example (example(example))|example|example|example(example|example|example(example|example))|example';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php