use strict;
my $str = '555a555a5555
555%555(5555
5555555855
555a555~5555
555 555 5555
555.555.5555
555,555,5555
555(any special char or letter in keyboard here)555(again anything here special char or letter)5555
555y555-5555
555/555/5555
555\\555\\5555
555]555[5555
555~555~5555';
my $regex = qr~(?<=\d)[^\d\n]+(?=\d)~p;
my $subst = '';
my $result = $str =~ s~$regex~$subst~rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html