const regex = /^(.*?\|){2}|(\|[^|]*){2}$/gm;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('^(.*?\\|){2}|(\\|[^|]*){2}$', 'gm')
const str = `One-1|two-2|Three-3|Four-4|Five-5
Six-6|Seven-7|Eight-8|Nine|Ten-10
Eleven-11|Twelve-12|Thirteen-13|Fourteen-14|Fifteen-15
Sixteen-16|Seventeen-17|Eighteen-18|Nineteen-19|Twenty-20`;
const subst = ``;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions