$re = '/((\W+?)?)((\w+?)?)(([aeiou|AEIOU]+?)?)(\w+?)(\W+?)/mx';
$str = '"When I went to school, they asked me what I wanted to be when I grew up. I wrote down "Happy." They told me I didn\'t understand the assignment, and I told them they didn\'t understand every life."
';
$subst = "\7\4ay ";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php