import Foundation
let pattern = #"(@PROG\$\s+)\([A-Z]+\)"#
let regex = try! NSRegularExpression(pattern: pattern, options: .anchorsMatchLines)
let testString = #"Background (UNASSIGNED): Previous study of ours showed that @PROG$ (ALI) and C-reactive protein (CRP) are independent significant prognostic factors in operable non-small cell lung cancer (NSCLC) patients."#
let stringRange = NSRange(location: 0, length: testString.utf16.count)
let substitutionString = #"\1@PROG$"#
let result = regex.stringByReplacingMatches(in: testString, range: stringRange, withTemplate: substitutionString)
print(result)
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Swift 5.2, please visit: https://developer.apple.com/documentation/foundation/nsregularexpression