$re = '/(?<=Box).*?(\d+)/mi';
$str = 'PO Box : **32322 EG LM01
po BoX : 34243 ffafa
POBox 32323 sdfodah dada
DAJD Po box : 33122 sdfa
SAJDAH pO boX 424234 DSFS';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php