$re = '/(?i)((?:Rs|EURO|DNR)\s*)\d+/';
$str = '0 RS 125 | password1
1 EURO 25 | password2
2 DNR 30 | password3';
$subst = "\g<1>100";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php