use strict;
my $str = '<img src="http://example/img/product/name/thumbs/100/img1.jpg" alt="описание фото1" width="100" height="100" caption="false" class="popup-img" />
<img src="http://example/img/product/name/thumbs/100/img2.jpg" alt="описание фото2" width="100" height="100" caption="false" class="popup-img left" />
<img src="http://example/img/product/name/thumbs/100/img2.jpg" alt="описание фото2" width="100" height="100" caption="false" class="wrong-class left" />';
my $regex = qr~<img src=".*?((/img/[^"]+)/thumbs/([^"]+))".*alt="(.*?)"[^>]*class="([^"]*popup-img[^"]*)"[^>]*>~mip;
my $subst = '<a class="$5" href="..$2/$3" title="$4" style="background: url(\'..$1\');-webkit-background-size: cover;background-size: cover;"></a>';
my $result = $str =~ s~$regex~$subst~rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html