use strict;
my $str = '<ul class="reset smalltext" id="msg_977743_extra_info">
<li class="stars"><img src="http://site123.com/forum/Themes/Curve_CC_css3/images/ranks/rank37.gif" alt="*" /></li>
<img src="http://site123.com/forum/Themes/Curve_CC_css3/images/useroff.gif" alt="Offline" />
src="http://site123.com/forum/index.php?PHPSESSID=0b057hm0efnc617b7463gs5ui4&action=dlattach;attach=5010;type=avatar" alt="" />';
my $regex = qr/(src=")(?![^"]+\?)(?:[^"]+\/|)/mp;
my $subst = '$1MyLocalPath/';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html