# If you'd like to omit non-matching lines from the result; add ';d' to the end of the expression.
sed -E 's/^https?:\\/\\/[\w.-]+(?<!\.domain\.edu)$/https:\/\/my.domain.edu/gm;t' <<< "https://www.google.com
http://not.the.best.example.org
http://another.bad.example.erewhon.edu
https://my.domain.com
https://your.page.domain.edu
http://good.domain.edu"
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for SED, please visit: https://www.gnu.org/software/sed/manual/html_node/The-_0022s_0022-Command.html