$re = '/(?<!\S)-?[$€£]?(\d+(?:[,.]\d+)?)(?!\S)/m';
$str = 'AAA PCSK-9, $111 -3,33
PCSK-9£12
PCSK-9 £12
Test €234 test€455 test -100,00 -€1999.00test';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php