use strict;
my $str = 'd016eb66c977d646642d491ae8461134:12345asdf
90ef258293ee214d1128abecd7b96f99:61231afad';
my $regex = qr/^[^:]+:/mp;
my $subst = '';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html