$re = '/^0[- ]*|[- ]+/m';
$str = '0 800-204-4000
0800-204 4000
0 800 -204 - 4000
800 204 4000';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php