const regex = /(comment_id=)(\d+)\|(\d+)\|([^|]+)\|([^|]+)\|(\d+)/;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('(comment_id=)(\\d+)\\|(\\d+)\\|([^|]+)\\|([^|]+)\\|(\\d+)', '')
const str = `comments={ts=2010-02-09T04:05:20.777+0000, comment_id=529590|2886|LOL|Baoping Wu|529360}
comments={ts=2010-02-09T04:05:20.777+0000, comment_id=529590, user_id = 2886, comment='LOL', user= 'Baoping Wu', post_commented=529360}`;
const subst = `$1$2, user_id = $3, comment='$4', user= '$5', post_commented=$6`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions