$re = '/(?-s)^([^:]+:).*(\R\1.*)+\R?/m';
$str = 'one1:text1
one1:text2
one3:text1
one2:text3
one2:text1
one4:text1';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php