$re = '/(.*?)\/([\d]{5})(.*)/';
$str = 'https://aabc.maternityneighborhood.com/limesurvey/index.php/survey/index/sid/682189/loadall/reload/scid/36636/loadname/cdahlhausen/loadpass/test/lang/en
';
$subst = "$1/123456$3";
$result = preg_replace($re, $subst, $str, 1);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php