const regex = /^(?:[^,]+,\s+){9}\K[^,]+/;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('^(?:[^,]+,\\s+){9}\\K[^,]+', '')
const str = `value1, value2, value3, value4, value5, value6, value7, value8, value9, value10`;
const subst = `x`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions