use strict;
my $str = '2 NO PEMJNUM 2 ALTOGETHER HOW MANY JOBS 216 - 217
1 REFERENCE PERSON 2 SPOUSE 3 CHILD 4 OTHER RELATIVE (PRIMARY FAMILY & UNREL) PRFAMTYP 2 FAMILY TYPE RECODE 155 - 156
5 UNABLE TO WORK PUBUS1 2 LAST WEEK DID YOU DO ANY 184 - 185
2 NO PEIO1COW 2 INDIVIDUAL CLASS OF WORKER CODE 432 - 433';
my $regex = qr/^(?:.*\b)?(\w+)\h*\b2\b.*/mp;
my $subst = '\\1';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html