const regex = new RegExp('[{} &+( )" =!.?.:.. / | » © : >< # « , 1 2 3 4 5 6 7 8 9 _ - + ; \\[ \\] %]', 'igu')
const str = ` :621 " :621 :1 ;" _ " :594 :25 4 8 0 :23 "സരàµâ€à´•àµà´•ാരàµâ€à´œàµ€à´µà´¨à´•àµà´•ാരàµà´Ÿàµ† à´¶à´®àµà´ªà´³à´‚ അറിയാനàµâ€ à´à´¾à´°àµà´¯à´®à´¾à´°àµâ€à´•àµà´•ൠഅവകാശമàµà´£àµà´Ÿàµà´µà´¿à´µà´°à´¾à´µà´•ാശകമàµà´®àµ€à´·à´¨àµâ€
:621 :4 0 3 0 ;" _ " :551 :16 :3`;
const subst = ``;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions