$re = '/(?=(main).*@(?:gmail|hotmail).com)/m';
$str = '123main456@gmail.com = match
123main@hotmail.com = match
someonemain@gmail.com = no match
123main456@agmail.com = match
123main@hotamail.com = match
someone@gmail.com = no match';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php