$re = '/(?i)^(?!.*\bvpn\b).*\budp\b.*$/m';
$str = ' /root/sumcommand -x -y udp
MATCH
/root/sumcommand VPN udp 12 4 2
NO MATCH
/root/sumcommand -x -y udp VPN 2 4 52
NO MATCH
/root/sumcommand udp ocean tools 1 5 2
MATCH';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php