$re = '/(<a[^>]+href=)(?:"https?:\/\/[^">]+"|\'https?:\/\/[^>\']+\')([^>]+>)/mius';
$str = ' Текст <a href="http://garlando.ru/shop/385/desc/nastolnyj-futbol-garlando-master-champion" target="_self">Ссылка</a>".
';
$subst = "$1\"#\"$2";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php