$re = '/(?i)^(.*?)_(\d{6}\D*\d{4})_(\d+)_(od|sd)_/m';
$str = '021-05-05_10-10-12-111_Nancy_Test_123456-1234_194456454390816_OD_2021042911270.pdf
';
$subst = "$2_servername1_$4_yyyy_mm_dd_ss_$1_$3_";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php