use strict;
my $str = 'Good
1
23
123
1234
12345
752892
1234567
Bad
123123456.000000
12a3123456.0000000000
123456.12345a12345';
my $regex = qr/.*[a-zA-Z.].*(*SKIP)(*FAIL)|\B(?=(\d{3})+(?!\d))/mp;
my $subst = ',';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html