$re = '/^(?=.*[\p{Script=Hiragana}\p{Script=Katakana}\p{Script=Han}])[\p{Script=Hiragana}\p{Script=Katakana}\p{Script=Han}a-zA-Z-,.。、!!??@@・\'’0-9 ]+$/mu';
$str = 'パイソンが得意です
pythonが得意です
I\'m good at python.';
preg_match_all($re, $str, $matches, PREG_SET_ORDER, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php