use strict;
my $str = 'ABC-ABC/ABC-ABC
ABC-ABC/DEF-DEF
GHI/GHI
JKL/JKLM
A/B-C';
my $regex = qr/^([^\/]+)\/(?:\1$\r?\n?)?/mp;
my $subst = '';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html