$re = '/(?:\/|-|\+|\:|^|\(|\)| ) ?(\d+)/m';
$str = '4/13/2022 2:20:03 pm from our side a more detailed analysis4 +7 (495) 797-8700 77-8282';
$subst = " ";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php