$re = '/\s*#.*/m';
$str = '1.6 # blah blah blah
# fjsadfklj slkjf yes 3.4
1.8*
1.9 1.10 #blah
#blah
1.11';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php