use strict;
my $str = '2^64
asdgaf1_hsg534
asdfh23_hsjd12
dgshg_jhfsd86
test
1
testing 1234 testing 1 test4
testing 1234 testing 123';
my $regex = qr/^.*[^\d\r\n](\d+)/mp;
my $subst = '\\1';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html